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Il plasma arricchito in piastrine: le domande in sospeso



1. Angelone M, Conti V, Biacca C et coll. The contribution of adipose tissue-derived mesenchymal stem cells and platelet-rich plasma to the treatment of chronic equine laminitis: a proof of concept. Int. J. Mol. Sci. 2017;18(10):2122.

2. Anitua M, Sanchez E, Nurden A et coll. New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol. 2006;24(5):227-234.

3. Argüelles D, Carmona JU, Climent F et coll. Autologous platelet concentrates as a treatment for musculoskeletal lesions in five horses. Vet. Rec. 2008;162(7):208-211.

4. Assoian RK, Komoriya A, Meyers CA et coll. Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization. J. Biol. Chem. 1983;258(11):7155-7160.

5. Brossi PM, Moreira JJ, Machado TS et coll. Platelet-rich plasma in orthopedic therapy: a comparative systematic review of clinical and experimental data in equine and human musculoskeletal lesions. BMC Vet. Res. 2015;11:98.

6. Camargo Garbin L, Lopez C, Carmona JU. A critical overview of the use of platelet-rich plasma in equine medicine over the last decade. Front. Vet. Sci. 2021;8:641818.

7. Cao Y, Zhu X, Zhou R et coll. A narrative review of the research progress and clinical application of platelet-rich plasma. Ann. Palliat. Med. 2021;10(4):4823-4829.

8. Carmona JU, Argüelles D, Climent F et coll. Autologous platelet concentrates as a treatment of horses with osteoarthritis: a preliminary pilot clinical study. J. Equine Vet. Sci. 2007;27(4):167-170.

9. Carter CA, Jolly DG, Worden CE Sr et coll. Platelet-rich plasma gel promotes differentiation and regeneration during equine wound healing. Exp. Mol. Pathol. 2003;74(3):244-255. 10. Colombo I, Mislei B, Mari G et coll. Effect of platelet lysate on uterine response of mares susceptible to persistent mating-induced endometritis. Theriogenology. 2022;179:204-210.

11. Dawod A, Miro J, Elbaz HT et coll. Effect of intrauterine infusion of equine fresh platelets-rich plasma (PRP) or lyophilized PRP (L-GFequina) on ovarian activity and pregnancy rate in repeat breeder purebred arabian mares. Animals (Basel). 2021;11(4):1123.

12. De Souza MV, Silva MB, Pinto J de O et coll. Immunohistochemical expression of collagens in the skin of horses treated with leukocyte-poor platelet-rich plasma. Biomed Res. Int. 2015;2015:893485.

13. Dohan Ehrenfest DM, Andia I, Zumstein MA et coll. Classification of platelet concentrates (platelet-rich plasmaPRP, platelet-rich fibrin-PRF) for topical and infiltrative use in orthopedic and sports medicine: current consensus, clinical implications and perspectives. Muscles Ligaments Tendons J. 2014;4(1):3-9. 

14. Everts PA, Knape JT, Weibrich G et coll. Platelet-rich plasma and platelet gel: a review. J. Extra. Corpor. Technol. 2006;38(2):174-187.

15. Faillace V, Tambella AM, Fratini M et coll. Use of autologous platelet-rich plasma for a delayed consolidation of a tibial fracture in a young donkey. J. Vet. Med. Sci. 2017;79(3):618-622. 

16. Giraldo CE, López C, Álvarez ME et coll. Effects of the breed, sex and age on cellular content and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel. BMC Vet. Res. 2013;9:29.

17. Jiménez-Aristazábal RF, Carmona JU, Prades M. Changes on the structural architecture and growth factor release, and degradation in equine platelet-rich fibrin clots cultured over time. J. Equine Vet. Sci. 2019;82:102789.

18. Jiménez-Aristizabal RF, López C, Álvarez ME et coll. Long-term cytokine and growth factor release from equine platelet-rich fibrin clots obtained with two different centrifugation protocols. Cytokine. 2017;97:149-155.

19. Kaplan DR, Chao FC, Stiles CD et coll. Platelet alpha granules contain a growth factor for fibroblasts. Blood. 1979;53(6):1043-1052.

20. Knott LE, Fonseca-Martinez BA, O’Connor AM et coll. Current use of biologic therapies for musculoskeletal disease: a survey of board-certified equine specialists. Vet. Surg. 2022;51(4):557-567.

21. Kon E, Di Matteo B, Delgado D et coll. Platelet-rich plasma for the treatment of knee osteoarthritis: an expert opinion and proposal for a novel classification and coding system. Expert Opin. Biol. Ther. 2020;20(12):1447-1460.

22. Leonardi F, Angelone M, Biacca C et coll. Platelet-rich plasma combined with a sterile 3D polylactic acid scaffold for postoperative management of complete hoof wall resection for keratoma in four horses. J. Equine Vet. Sci. 2020;92:103178.

23. Moher D, Liberati A, Tetzlaff J et coll. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.

24. Montano C, Auletta L, Greco A et coll. The use of platelet-rich plasma for treatment of tenodesmic lesions in horses: a systematic review and meta-analysis of clinical and experimental data. Animals (Basel). 2021;11(3):793.

25. Monteiro SO, Lepage OM, Theoret CL. Effects of platelet-rich plasma on the repair of wounds on the distal aspect of the forelimb in horses. Am. J. Vet. Res. 2009;70(2):277-282. 26. Pereira RCDF, De La Côrte FD, Brass KE et coll. Evaluation of three methods of platelet-rich plasma for treatment of equine distal limb skin wounds. J. Equine Vet. Sci. 2019;72:1-7.

27. Qian Y, Han Q, Chen W et coll. Platelet-rich plasma derived growth factors contribute to stem cell differentiation in musculoskeletal regeneration. Front. Chem. 2017;5:89. 

28. Sampson S, Gerhardt M, Mandelbaum B. Platelet rich plasma injection grafts for musculoskeletal injuries: a review. Curr. Rev. Musculoskelet. Med. 2008;1(3-4):165-174. 

29. Schnabel LV, Mohammed HO, Miller BJ et coll. Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum superficialis tendons. J. Orthop. Res. 2007;25(2):230-240.

30. Segabinazzi LG, Friso AM, Correal SB et coll. Uterine clinical findings, fertility rate, leucocyte migration, and COX-2 protein levels in the endometrial tissue of susceptible mares treated with platelet-rich plasma before and after AI. Theriogenology. 2017;104:120-126. 

31. Smith JJ, Ross MW, Smith RK. Anabolic effects of acellular bone marrow, platelet rich plasma, and serum on equine suspensory ligament fibroblasts in vitro. Vet. Comp. Orthop. Traumatol. 2006;19(1):43-47.

32. Waselau M, Sutter WW, Genovese RL et coll. Intralesional injection of platelet-rich plasma followed by controlled exercise for treatment of midbody suspensory ligament desmitis in standardbred racehorses. J. Am. Vet. Med. Assoc. 2008;232(10):1515-1520.

Abbonati per accedere

Dal web internazionale

Dolore e disfunzione cervicale equina: patologia, diagnosi e trattamento

L'interesse per il rachide cervicale come causa di dolore o disfunzione sta diventando sempre più importante per molti ippiatri. Molti cavalli vengono infatti visitati per scarse prestazioni, mentre altri presenteranno comportamenti anomali, talora pericolosi.


Formazione a distanza


Corsi FAD per ippiatri:

- Le micosi delle tasche gutturali

- Ciclo estrale e diagnosi di gravidanza

- Iter diagnostico del cavallo in colica


I corsi, che non erogano crediti formativi, sono accessibili dalla piattaforma e-learning nella sezione "Eventi non accreditati"